Insights into the role of Moringa oleifera in ameliorating acetaminophen induced hepatotoxicity in Nile tilapia, Oreochromis niloticus.
L. P. Rema and C. B. Liji
The study was aimed to investigate the hepato-protective effect of Moringa oleifera in Nile tilapia (Oreochromis niloticus) exposed to acetaminophen. Fishes exposed to sub-lethal concentration of acetaminophen for 96 hours, were fed on feed incorporated with moringa leaf, for 21 days. Histological studies of liver of fish fed with M. oleifera leaf incorporated feed , for 21 days after 96-hour acetaminophen exposure showed significant reparative changes when compared to the control. The experiment indicate that dietary supplementation of moringa leaf had hepatoprotective effect in Nile tilapia exposed to acetaminophen.
Keywords: Acetaminophen, Moringa oleifera, histopathology, hepatoprotection