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Coagulation profile in two nephropathic dogs
M. V. Anjaly, K. R. Sindhu, N. P. Usha, S. Ajithkumar and K. Justin Davis

doi: https://doi.org/10.51966/jvas.2021.52.4.409-413

Journal of Veterinary and Animal Sciences.2021.52 (4):409-413.

Author Details

M. V. Anjaly: M.V.Sc. scholar, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary & Animal Sciences, Mannuthy, Thrissur, Kerala – 680651 Kerala Veterinary and Animal Sciences University, India.

K. R. Sindhu: Assistant Professor, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary & Animal Sciences, Mannuthy, Thrissur, Kerala – 680651 Kerala Veterinary and Animal Sciences University, India.

N. P. Usha: Professor and Head, Department of Clinical Veterinary Medicine, Ethics and Jurisprudence, College of Veterinary & Animal Sciences, Mannuthy, Thrissur, Kerala – 680651 Kerala Veterinary and Animal Sciences University, India.

S. Ajithkumar: Professor and Head, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary & Animal Sciences, Pookode,  Kerala Veterinary and Animal Sciences University, India.

K. Justin Davis: Assistant Professor, Department of Veterinary Epidemiology and Preventive Medicine, College of Veterinary & Animal Sciences, Mannuthy, Thrissur, Kerala – 680651 Kerala Veterinary and Animal Sciences University, India.

Article History

Received: 08.03.2021 Accepted: 30,05.2021 Published: 15.12.2021

Corresponding author: M. V. Anjaly

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Citation: Anjaly, M. V., Sindhu, K. R., Usha, N. P., Ajithkumar, S. and Justin Davis, K. 2021. Coagulation profile in two nephropathic dogs. J. Vet. Anim. Sci. 52(4):409-413   DOI: https://doi.org/10.51966/jvas.2021.52.4.409-413

 



Abstract


Coagulatory abnormalities are common in renal dysfunction in humans. The studies on coagulatory abnormalities in renal failure in dogs are limited. The present paper deals with coagulation profile in acute and chronic kidney disease in dogs. The haemostatic defects observed in acute renal dysfunction included thrombocytopaenia, prolonged capillary bleeding time (CBT), elevated D-Dimer and hypoantithrombinemia which indicated a hypercoagulable state. Prolongation of prothrombin time (PT), activated partial thromboplastin time (aPTT), elevated D-Dimer concentration and hypoantithrombinemia in chronic kidney disease indicated the presence of hypocoagulable state.