REVIEW ARTICLES
Clostridioides difficile infection: An emerging zoonotic disease
Clostridioides difficile infection: An emerging zoonotic disease
doi: : https://doi.org/10.51966/jvas.2022.53.2.129-142
Journal of Veterinary and Animal Sciences.2022.53(2):129-142.
Author Details
Abraham Joseph Pellissery: Department of Animal Science, University of Connecticut, Storrs, CT 06269, USA
Poonam Gopika Vinayamohan: Department of Veterinary Preventive Medicine, Ohio State University, Columbus, OH 43210, USA
Kumar Venkitanarayanan: Department of Animal Science, University of Connecticut, Storrs, CT 06269, USA
Article History
Received: 21.12.2021, Accepted: 20.01.2022, Published online: 01.06.2022
Corresponding author: Kumar Venkitanarayanan
e-mail: : kumar.venkitanarayanan@uconn.edu
Citation: : Pellissery, A.J., Vinayaohan, P.G. and Venkitanarayanan, K. 2022. Clostridioidesdifficile infection: an emergingzoonotic disease. J.Vet. Anim. Sci. 53(2): 129-142. DOI: https://doi.org/10.51966/jvas.2022.53.2.129-142
Abstract
Clostridioides difficile is a spore-forming enteric pathogen of public health concern causing a toxin-mediated diarrhea in humans. In several countries, the bacterium has evolved as a hypervirulent, antibiotic-resistant pathogen with concerns for its nosomial and communityassocaited routes for disease transmission. Although the exact routes for community-associated infection have not been substantially elucidated, recent surveillance and genetic diversity analysis of community-borne isolates indicate for the potential spillover of the pathogen amongst the human, animal and environment interfaces. This review article highlights the importance of One Health approach for the control of C. difficile infection.
Keywords: Clostridioides difficile, zoonosis
