RESEARCH ARTICLES
A prospective study on haematobiochemical aspects of atopic dermatitis in dogs
V.R. Ambily, N.P. Usha, S. Ajithkumar, C. Deepa, P. Vinu David , S. Maya, T.V. Aravindakshan and B. Dhanush Krishna
doi: https://doi.org/10.51966/jvas.2022.53.4.731-739
Journal of Veterinary and Animal Sciences.2022.53(4):731-739.
Author Details
V.R. Ambily : Assistant Professor, Department of Clinical Veterinary Medicine College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, India
N. P. Usha : Professor and Head, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, Mannuthy - 680 651, Kerala Veterinary and Animal Sciences University, Kerala, India.
S. Ajithkumar : Professor, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, Mannuthy - 680 651, Kerala Veterinary and Animal Sciences University, Kerala, India.
C. Deepa : Veterinary surgeon
P. Vinu David : Associate Professor, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, Mannuthy - 680 651, Kerala Veterinary and Animal Sciences University, Kerala, India.
S. Maya : Professor, Department of Veterinary Anatomy and Histology, College of Veterinary and Animal Sciences, Mannuthy - 680 651, Kerala Veterinary and Animal Sciences University, Kerala, India.
T.V. Aravindakshan : Professor and Head, Department of Animal Breeding and Genetics, College of Veterinary and Animal Sciences, Mannuthy - 680 651, Kerala Veterinary and Animal Sciences University, Kerala, India.
B. Dhanush Krishna : Assistant Professor, Department of Veterinary Pathology, College of Veterinary and Animal Sciences, Mannuthy - 680 651, Kerala Veterinary and Animal Sciences University, Kerala, India.
Article History
Received: 10.08.2022, Accepted: 15.09.2022, Published online: 31.12.2022
Corresponding author: V.R. Ambily
e-mail : ambily.vr@kvasu.ac.in
Citation: Ambily,V.R., Usha,N.P., Ajithkumar,S., Deepa,C., Vinu David, P., Maya,S., Aravindakshan,T.V. and Dhanush, K.B. 2022. A prospective study on haemato-biochemical aspects of atopic dermatitis in dogs. J. Vet. Anim. Sci. 53(4): 731-739
DOI: https://doi.org/10.51966/jvas.2022.53.4.731-739
Abstract
A prospective study on haemato-biochemical aspects of canine atopic dermatitis was conducted in the Department of Clinical Veterinary Medicine, College of Veterinary and Animal Sciences, Mannuthy during the period from 2019 to 2021. Sixteen dogs diagnosed with atopic dermatitis using characteristic clinical (Favrot’s) criteria with exclusion of other pruritic skin diseases, together with elevated Ig E levels and ten healthy animals formed the subjects for the present study. Whole blood samples were collected from atopic and healthy controls and haematobiochemical parameters were estimated. Haemato-biochemical studies of atopic dogs revealed anaemia with leukocytosis, neutrophilia and eosinophilia and hypoalbuminaemia with reduced AG ratio. Absolute eosinophil count that was found positively correlated with neutrophil to lymphocyte ratio (NLR) in atopic dogs, is of diagnostic significance in quantifying inflammatory response which helps in instituting customized treatment to atopic animals in clinical practice. Hypoalbuminaemia observed in atopic animals in the present study indicates the need for nutrient supplementation in the therapeutic protocol of the disease.
Keywords: Atopic dermatitis, haemogram, neutrophil to lymphocyte ratio, dogs