RESEARCH ARTICLES

Effects of intravenous lignocaine on anaesthetic parameters in cattle under dexmedetomidine-butorphanol-ketaminemidazolam- isofluraneanaesthesia
V. Jayakrishnan, S. Sudheesh Nair, Reji Varghese, Soumya Ramankutty, Preethy John and K. D. John Martin

doi: https://doi.org/10.51966/jvas.2023.54.1.198-203

Journal of Veterinary and Animal Sciences.2023.54(1):198-203

Author Details

V. Jayakrishnan: MVSc. scholar, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680651, Kerala Veterinary and Animal Sciences University, Pookode, Kerala, India.

S. Sudheesh Nair : Assistant Professor, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680651, Kerala Veterinary and Animal Sciences University, Pookode, Kerala, India.

Reji Varghese : Assistant Professor, Teaching Veterinary Clinical Complex, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680651, Kerala Veterinary and Animal Sciences University, Pookode, Kerala, India.

Soumya Ramankutty: Assistant Professor, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680651, Kerala Veterinary and Animal Sciences University, Pookode, Kerala, India.

Preethy John : Assistant Professor, Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680651, Kerala Veterinary and Animal Sciences University, Pookode, Kerala, India.

 

K.D. John Martin : Professor and Head, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur-680651, Kerala Veterinary and Animal Sciences University, Pookode, Kerala, India.

Article History

Received: 08.11.2022 Accepted: 29.12.2022 Published online: 31.03.2023

Corresponding author: V. Jayakrishnan

e-mail : jayakrishnanv07@gmail.com

Citation :Jayakrishnan,V., Sudheesh Nair,S., Reji,V.,Soumya,R. Preethy,J. and John Martin,K.D. 2023. Effects of intravenous lignocaine on anaesthetic parameters in cattle under dexmedetomidinebutorphanol- ketamine-midazolam-isofluraneanaesthesia. J. Vet. Anim. Sci. 54(1):198-203

DOI: https://doi.org/10.51966/jvas.2023.54.1.198-203



Abstract


The present study was conducted for clinical evaluation of a multimodal anaesthetic protocol using butorphanol-dexmedetomidine-midazolam-ketamine-isoflurane and lignocaine continuous rate infusion (CRI) in six cross-bred female cattle. Preanaesthetics used were butorphanol and dexmedetomidine which were administered intravenously at dose rates of 0.05 mg/kg and 1 μg/ kg body weight, respectively. Ketamine and midazolam were intravenously administered at dose rates of 4.0 and 0.2 mg/kg body weight respectively, to induce anaesthesia. Isoflurane was used to maintain anaesthesia after endotracheal intubation, at a concentration of 1.05 ± 0.97 per cent concentration in 100 per cent oxygen using a large animal anaesthesia machine. Simultaneously, intravenous lignocaine was administered at a bolus dose of 2 mg/kg body weight followed by a CRI of 3 mg/kg body weight/hour using a volumetric infusion pump. Isoflurane sparing effect of intravenous lignocaine reduced the required concentration of isoflurane for maintenance. The third plane of surgical anaesthesia was maintained and various surgical procedures were done. Recovery was smooth. Other than the mild regurgitation of ruminal fluid in an animal, no anaesthetic complications were noticed.

Key words: Cattle, lignocaine, isoflurane sparing