RESEARCH ARTICLES
Evaluation of electrocardiographic and serum biochemical changes in arrhythmias associated with renal diseases of dogs
U. S. Remya Krishna, Arun George, Usha Narayana Pillai, Sindhu K. Rajan and Suresh N. Nair
doi: https://doi.org/10.51966/jvas.2023.54.2.419-427
Journal of Veterinary and Animal Sciences.2023.54(2):419 - 427
Author Details
U. S. Remya Krishna : MVSc Scholar, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, India
Arun George : Assistant Professor, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, India
Usha Narayana Pillai : Professor and Head, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, India
Sindhu K. Rajan : Assistant Professor, Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, India
Suresh N. Nair : Associate Professor, Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680 651, Kerala Veterinary and Animal Sciences University, Kerala, India
Article History
Received: 09.11.2022 Accepted: 28.12.2022 Published online: 30.06.2023
Corresponding author: U. S. Remya Krishna
e-mail : remyakrishna549@gmail.com
Citation: Krishna, R.U.S., George, A., Pillai, U. N., Rajan, S. K. and Nair, S. N. 2023. Evaluation of electrocardiographic and serum biochemical changes in arrhythmias associated with renal diseases of dogs. J. Vet. Anim. Sci. 54(2):419-427
DOI: https://doi.org/10.51966/jvas.2023.54.2.419-427
Abstract
The present study was conducted to investigate electrocardiographical (ECG) and haemato-biochemical changes in arrhythmia associated with renal diseases in dogs. The dogs with renal affections confirmed through appropriate diagnostic methods were selected and screened for arrhythmia. The ECG and haemato-biochemical parameters of twenty dogs with arrhythmia were compared with that of the control group and ECG parameters were statistically correlated with the haemato-biochemical parameters for correlation studies. It was found that the occurrence of arrhythmia was 51.2 per cent in renal diseases. Arrhythmia was more predominant in dogs with chronic kidney disease (CKD) followed by acute kidney injury (AKI). Sinus arrhythmia followed by first-degree AV block and wandering pacemaker were the common types of arrhythmias observed. A significant increase in R-R interval and a decrease in heart rate was noticed in comparison. The haemato-biochemical analysis revealed anaemia, leukocytosis with neutrophilia, elevated blood urea nitrogen (BUN), creatinine and magnesium level. A significant positive correlation was noticed between haemoglobin, volume of packed red cells (VPRC) and red blood cell count (RBC) with T amplitude and, creatinine and BUN levels with corrected Q-T interval. A significant negative correlation was noticed between VPRC, RBC and haemoglobin with the corrected QT interval. The present study revealed ECG and haemato-biochemical parameters had a significant role in renal diseases in dogs which might help in the early diagnosis and proper management of arrhythmia associated with renal diseases.
Keywords: Renal disease, Arrhythmia, electrocardiography, correlation studies