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Lamellar keratoplasty using decellularised porcine cornea as an acellular scaffold graft for surgical management of deep corneal ulcer in a dog
A. Aswathy Mohan, S. Anoop, K. D. John Martin, Laiju M. Philip, V. N. Vasudevan and Ashlin Michael

doi: https://doi.org/10.51966/jvas.2023.54.2.600-603

Journal of Veterinary and Animal Sciences.2023.54(2):600-603

Author Details

A. Aswathy Mohan : MVSc Scholar, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680651, Kerala Veterinary and Animal Sciences University, Kerala, India

S. Anoop : Professor and Head, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Pookode, Kerala Veterinary and Animal Sciences University, Kerala, India

K. D. John Martin : Professor and Head, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680651, Kerala Veterinary and Animal Sciences University, Kerala, India

Laiju M. Philip : Assistant Professor, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680651, Kerala Veterinary and Animal Sciences University, Kerala, India

V. N. Vasudevan : Associate Professor and Head, Department of Livestock Products Technology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680651, Kerala Veterinary and Animal Sciences University, Kerala, India

Ashlin Michael : MVSc Scholar, Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680651, Kerala Veterinary and Animal Sciences University, Kerala, India

Article History

Received: 09.11.2022 Accepted: 20.02.2023 Published online: 30.06.2023

Corresponding author: S. Anoop

e-mail : anoop@kvasu.ac.in

Citation: Aswathy, M.A., Anoop, S., John, M.K.D., Laiju M.P., Vasudevan, V.N. and Ashlin, M. 2023. Lamellar keratoplasty using decellularised porcine cornea as an acellular scaffold graft for surgical management of deep corneal ulcer in a dog. J. Vet. Anim. Sci. 54(2):600-603

DOI: https://doi.org/10.51966/jvas.2023.54.2.600-603



Abstract


Corneal ulcers are one of the most common eye affection in domestic animals, especially dogs. In preclinical studies, porcine corneas were used regularly as an animal model due to its relative similarity to human cornea and its availability in great numbers from slaughter houses. In the present study, decellularised porcine cornea was used for corneal grafting as an acellular scaffold graft material in a case presented with deep corneal ulcer. The efficiency of the graft material was analysed on the day of presentation, days 7, 14, 21 and 60 post grafting, based on corneal clarity, oedema, neovascularisation, pigmentation, visual function and scar tissue formation. Decellularised porcine corneas were found to be very convenient to handle during surgery, provided good tectonic support, had good tissue biocompatibility and produced only mild to moderate graft opacity.

Keywords: Decellularised porcine cornea, deep corneal ulcers, grafting