RESEARCH ARTICLES
5. Assessment of foetal lung surfactant in amniotic fluid of dogs by bubble test, to evaluate foetal maturity
D.S. Suprith, M.P. Unnikrishnan, M.O. Kurien, B. Bibin Becha and Binu K. Mani
Journal of Veterinary and Animal Sciences.2020. 51(2):128-131.
Author Details
D.S. Suprith: PG Scholar, Department of Animal Reproduction, Gynaecology and Obstetrics, College of Veterinary and Animal Sciences, Mannuthy, Kerala Veterinary and Animal Sciences University, Kerala, India.
M.P. Unnikrishnan: Assistant Professor, Department of Animal Reproduction, Gynaecology and Obstetrics, College of Veterinary and Animal Sciences, Mannuthy, Kerala Veterinary and Animal Sciences University, Kerala, India.
M.O. Kurien: Professor and Head (Rtd.), Department of Animal Reproduction, Gynaecology and Obstetrics, College of Veterinary and Animal Sciences, Mannuthy, Kerala Veterinary and Animal Sciences University, Kerala, India.
B. Bibin Becha: Professor, Department of Animal Reproduction, Gynaecology and Obstetrics, College of Veterinary and Animal Sciences, Mannuthy, Kerala Veterinary and Animal Sciences University, Kerala, India.
Binu K Mani: Assistant Professor, Department of Veterinary Microbiology, College of Veterinary and Animal Sciences, Pookode, Kerala Veterinary and Animal Sciences University, Kerala, India.
Article History
Received: 07.08.2019, Accepted: 15.10.2019, Published online: 01.07.2020
Corrersponding author: D.S. Suprith
e-mail: suprithraj4@gmail.com
Citation: Suprith, D.S., Unnikrishnan, M.P., Kurien, M.O., Bibin, B. B. and Binu, K. M. 2020. Assessment of foetal lung surfactant in amniotic fluid of dogs by bubble test, to evaluate foetal maturity. .J. Vet. Anim. Sci. 51(2): 128-131.
Abstract
Study was conducted to determine the reliability of bubble test for assessment of lung surfactant in amniotic fluid and its application in clinical level to judge the foetal maturity. Amniotic fluid samples were collected from the foetuses of dogs undergoing elective caesarean section (Group I) at term and from the foetuses of dogs undergoing ovariohysterectomy at different stages of gestation, following misalliance (Group II). All the samples from neonates of Group I were found positive for bubble test, with variable grades ranging from two to four. All the samples from Group II foetuses were found negative for bubble test, with grade of zero and one. The results signify the presence of adequate foetal surfactant in amniotic fluid of mature foetuses when compared to that of immature foetuses and also suggest the potential practical utility of bubble test for foetal maturity assessment, particularly for timing elective induction of whelping or timing of caesarean delivery.
Keywords: Bubble test, Foetal maturity, Amniotic fluid, Surfactant, Gestation
