RESEARCH ARTICLES

ANTIFUNGAL 1?FFECT OF SPHAERAN'IHUS INDICUS: A CLINICO -LABORATORY STUDY
P. Vinu David, P.G. Baby, S. Ajithkumar, P.C. Alex

Spltaera~athtcs i~adicacs (Mal. Adakkamaniyan) is a much branched, annual herb with its stem winged, wings dentate; leaves alternate; heads globose and purplish pink and is distributed tht-oughout the plains in India. It has been used as an indigenous drug fot-the treatment of ring worm in human beings (Agharkar, 1953). But in veterinary practice its use as an antifungal agent has not yet documented. Hence this study was undertaken to evaluate the antifungal effect of S. i~zdicus by i~z vivo and i~z vr'tro studies against dei-matophytes in dogs. Its therapeutic effect was also compared with the modern antifungal agent like ketoconazole.



Abstract