Volume: 53 Issue: 1
Year: 2022, Page: 18-21, Doi: https://doi.org/10.51966/jvas.2022.53.1.18-21
Received: March 18, 2021 Accepted: May 5, 2021 Published: March 31, 2022
Extensive research is being carried out to replicate different aspects of burn injury, understand the unique pathophysiology as well as to develop novel treatment modalities for the burn wounds. Adequate research using different burn models thus play a major role in the development of novel treatments. One of the major constraints in burn animal model is a lack of reproducible burn inducing device which could be used for producing uniform burn wounds. Here we have developed simple, reproducible burn inducing device with temperature control for the creation of uniform burn wounds in animal models.
Keywords: Burn, burn inducing device, burn models, uniform burn wound
Abdeldjelil, M.C., Messai, A., Boudebza, A. and Beghoul, S. 2017. Practical aspects to generate cutaneous experimental burns in a rat model. Pharm. Lett. 9(1): 70-84.
Cai, E.Z., Ang, C.H., Raju, A., Tan, K.B., Hing, E.C.H., Loo, Y., Wong, Y.C., Lee, H., Lim, J., Moochhala, S.M. and Hauser, C.A. 2014. Creation of consistent burn wounds: a rat model. Arch. Plast. Surg. 41(4): 317-324.
Mitsunaga Junior, J.K., Gragnani, A., Ramos, M.L.C. and Ferreira, L.M. 2012. Rat an experimental model for burns: a systematic review. Acta Cir. Bras. 27(6): 417-423.
Sayeed, M.M. 2005. Inflammatory/cardiovascular-metabolic responses in a rat model of burn injury with superimposed infection. Shock. 24: 40-44.
Shukla, S.K., Sharma, A.K., Shaw, P., Kalonia, A., Yashavarddhan, M.H. and Singh, S. 2020. Creation of rapid and reproducible burn in animal model with a newly developed burn device. Burns. 46 (5): 1142-1149.
Singer, A.J., Berruti, L., Thode Jr, H.C. and McClain, S.A. 2009. Standardized burn model using a multiparametric histologic analysis of burn depth. Acad. Emerg. Med. 7(1): 1-6.
Tehrani, S., Lotfi, P., Tehrani, S., Jangholi, E., Aryan, H. and Aidun, A. 2016. Healing effect of sesame ointment on second-degree burn wound in rats. Galen Med. J. 5: 56-62.
Tiwari, V.K. 2012. Burn wound: how it differs from other wounds?. Indian J. Plastic Surg. 45 (2):364-372.
Van Egmond, C.F. 1991. Heater utilizing copper-nickel alloy core, U.S. Patent No. 5,060,287.
© 2022 Anjana et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Anjana, S., Abhijith, P., Reji, V., Anandu, R., Dinesh, P.T. and George, C. 2022. Burn inducing device with temperature control to generate experimental cutaneous burn wounds in animal models. J. Vet. Anim. Sci. 53(1): 18-21
DOI: https://doi.org/10.51966/jvas.2022.53.1.18-21