Volume: 55 Issue: 4
Year: 2024, Page: 788-795, Doi: https://doi.org/10.51966/jvas.2024.55.4.788-795
Received: Sept. 25, 2024 Accepted: Nov. 6, 2024 Published: Dec. 31, 2024
Feline patients presenting with body cavity effusions are frequently encountered in veterinary clinical practice.
Klebsiella spp. were isolated and identified from the septic effusions of three out of 23 cats with body cavity effusions.
The morphological and biochemical identification was further confirmed through genus-specific PCR. Sequencing of
the PCR products revealed the organism to be Klebsiella pneumoniae. Antibiotic susceptibility profiling of the organism
indicated maximum susceptibility to doxycycline and enrofloxacin, while amoxicillin-clavulanate was the least effective.
Haematological analysis revealed elevated total leukocyte count, with a marked increase in both the absolute neutrophil
count and neutrophil percentage in all three cases of septic effusion. Thrombocytopenia was evident, while total erythrocyte
count, haemoglobin, and haematocrit levels remained relatively unchanged. Biochemical analysis revealed significant
increase in AST (3/3), increase in BUN (3/3), increased ALP (1/3) and elevated TP (2/3), with hypoalbuminemia in one
case. The total nucleated cell count (TNCC) in all samples exceeded 100,000 cells/μL, indicating a robust inflammatory
response characteristic of septic effusions.
Keywords: Klebsiella spp., amoxicillin-clavulanate, septic effusions
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© 2024 Raina et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0
International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in
any medium, provided the original author and source are credited.
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J. Vet. Anim. Sci. 55 (4):788-795