Journal of Veterinary and Animal Sciences

Volume: 54 Issue: 4

  • Open Access
  • Research Article

Effect of fermentation on antibacterial activity of milk from Vechur and Kasargod Dwarf cattle

J. S. Pooja1*, C. R. Rachana2, S. Panicker Aiswarya3 and K. J. Sana4

1. M.Sc. Scholar, Dept. of Veterinary Biochemistry, College of Veterinary and Animal Sciences, Mannuthy, Thirssur-680 651.
2. Assistant professor, Dept. of Dairy Chemistry, College of Dairy Science and Technology, Thiruvananthapuram -695040.
3. Assistant professor, Dept. of Dairy Microbiology, College of Dairy Science and Technology, Thiruvananthapuram -695040.
4. M-Tech Scholar, Dept. Of Dairy Chemistry, Verghese Kurien Institute of Dairy and Food Technology, Mannuthy, Thrissur- 680 651.

*Corresponding author: [email protected], Ph. +91-8129108293

Year: 2023, Page: 966-972, Doi:

Received: March 22, 2023 Accepted: July 29, 2023 Published: Dec. 31, 2023


The search for alternative therapeutics is on the rise on account of widespread bacterial resistance to numerous conventional antibiotics. Bioactive peptides produced by lactic acid bacteria found in natural sources such as fermented dairy products have attracted attention as a possible source of biotherapeutic peptides. Bioactive peptides released in fermented milk, on the other hand, is dependent on the proteolytic activities of the cultures used. As a result, this study was carried out to evaluate the effect of fermentation on antibacterial activity of milk from Vechur and Kasargod Dwarf cattle against pathogenic bacteria during 21-days storage period at 5°C. High-speed centrifugation was used to create water-soluble crude peptide extracts. The  water-soluble peptides from Kasargod Dwarf and Vechur cattle by fermentation showed maximum inhibition against Escherichia coli NCIM2685 and Salmonella enterica ATCC 6017. The zone of inhibition measured ranges from 5mm to 11mm throughout the storage period. However, both did not show zone of inhibition against Bacillus cereus ATCC 10876 and Staphylococcus aureus ATCC 25923 during 21 days of storage at pH 7.4.

Keywords: Vechur cattle, Kasargod Dwarf, antibacterial activity, bioactive peptides


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Cite this article

Pooja, J.S., Rachana, C.R., Aiswarya, S.P. and Sana, K.J. 2023. Effect of fermentation on antibacterial activity of milk from Vechur and Kasargod Dwarf cattle. J. Vet. Anim. Sci. 54(4):966-972