Volume: 56 Issue: 2
Year: 2025, Page: 387-392, Doi: https://doi.org/10.51966/jvas.2025.56.2.387-392
Received: Sept. 28, 2024 Accepted: Jan. 9, 2025 Published: June 30, 2025
Lumpy skin disease (LSD) is a notifiable disease caused by LSD virus belonging to the family Poxviridae
and Capripoxvirus genus. The disease is characterised by fever, lymphadenopathy and presence of skin nodules. This
article reports the occurrence of lumpy skin disease among Vechur cattle and its molecular confirmation. Two heifers in
a Vechur farm were presented with elevated body temperature and nodules of varying sizes on the skin of abdomen and
thorax region. Polymerase chain reaction was performed with primers targeting the viral attachment protein, P32 using
DNA extracted from skin nodules which yielded amplicons of 192 bp size specific for LSD virus. Haematological and
serum biochemical parameters were found to be within in the normal ranges. Histopathology of skin nodules revealed
pyogranulomatous myositis and fibrinous vasculitis. Successful treatment was provided with broad spectrum antibiotic,
anti-inflammatory drugs and topical antiseptic application. The findings of present study warrant the need for adopting
control measures against LSD, including vector control and vaccination in the indigenous breeds of cattle like Vechur.
Keywords: Haematology, serum biochemistry, histopathology, P32 gene, polymerase chain reaction
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© 2025 Manoj et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0
International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in
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Manoj, R.V., Tresamol, P.V., Preena, P., Manoj, M., Anoopraj, R., Justin Davis, K., Shyma, V.H. and Vijayakumar,
K. 2025. Occurrence and molecular confirmation of Lumpy skin disease among Vechur cattle in Kerala.
J. Vet. Anim. Sci. 56 (2):387-392