Volume: 56 Issue: 1
Year: 2025, Page: 1-7, Doi: https://doi.org/10.51966/jvas.2025.56.1.1-7
Received: Feb. 27, 2025 Accepted: March 14, 2025 Published: March 31, 2025
Three-dimensional (3D) bioprinting is a revolutionary biomedical technology that allows researchers to create custom 3D tissue models to study human organ physiology and disease pathobiology. Bioprinting utilizes bioinks containing living cells, biomaterials, and essential growth factors to construct complex, 3D tissue-like structures with remarkable precision. Their application in infectious disease research is particularly significant, as they replicate organs such as lungs, liver, skin, and intestines, allowing scientists to analyze pathogen-host interactions at cellular and tissue levels closely. By employing 3D bioprinting, researchers have successfully developed tissue models to study viral and bacterial infections, offering insights into pathogen evolution, immune responses, and therapeutic interventions. These models play a critical role in drug discovery by providing a physiologically relevant platform for testing the efficacy and safety of antimicrobial and antiviral drugs. Additionally, bioprinted tissues can minimize reliance on animal testing and improve species-specific drug response predictions. 3D bioprinted models are poised to transform infectious disease research and therapeutic development. Here, we give a perspective on 3D bioprinting and its applications in infectious disease modeling.
Keywords: 3D bioprinting, Infectious Diseases, Disease modeling, Organoids, Bioengineering
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© 2025 Soman et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0
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Soman, S.S., Kuchipudi, S.V. and Kumar, S. 2025. Advances in Infectious Disease Modeling: A perspective on
3D-Bioprinted Tissue Models to Study Host-Pathogen Interactions.
J. Vet. Anim. Sci. 56 (1):1-7