Journal of Veterinary and Animal Sciences

Volume: 55 Issue: 2

  • Open Access
  • Research Article

Management of deep corneal ulcer in a dog using autologous platelet rich fibrin (PRF) membrane

Ajin S. Kumar1*, Syam K. Venugopal1, Soumya Ramankutty1, Laiju M. Philip1, K. D.John Martin2 and K. S. Prasanna3

1. Department of Veterinary Surgery and Radiology College of Veterinary and Animal Sciences, Mannuthy, Thrissur- 680651 Kerala Veterinary and Animal Sciences University Kerala, India

2. University Veterinary Hospital, Kokkalai

3. Department of Veterinary Pathology, CVAS, Mannuthy

*Corresponding author: [email protected], Ph. 7907060861

Year: 2024, Page: 312-316, Doi: https://doi.org/10.51966/jvas.2024.55.2.312-316

Received: Sept. 21, 2023 Accepted: Jan. 11, 2024 Published: June 30, 2024

Abstract

A six-year-old male spitz dog was presented with deep corneal ulcer in left eye and cataractous changes in right eye. Menace response, cotton ball test and pupillary light reflex were found negative for both eyes. Fluorescein dye test was positive for left eye and no improvement was noticed on medical management. Hence, surgical intervention with platelet rich fibrin (PRF) membrane grafting was resorted to for the protection of the ulcer bed. Autologous platelet rich fibrin membrane was grafted over the corneal ulcer bed under general anaesthesia, followed by third eyelid membranoplasty. Topical antibiotic and anti-inflammatory drops were advised for five days post-operatively and the dog had an uneventful recovery.

Keywords: Autologous graft, corneal ulcer, platelet-rich fibrin membrane

References

Anoop, S., Devanand, C. B., Syam, K. V., Martin, J. K. D., Ajithkumar, S., Gleeja, L. and Ghosh, K. N. A. 2015. Pigmentary keratitis in dogs. Indian J. Vet. Res. 24: 31-33.

Antonia, N.A., Narayanan, M.K., Anoop, S., Devanand, C.B., Martin, J. and Venugopal, S.K. 2014. Occurrence of ophthalmic disorders in dogs. Indian J. Vet. Res. 23: 21-24.

Can, M.E., Can, G.D., Cagil, N., Cakmak, H.B. and Sungu, N. 2016. Urgent therapeutic grafting of platelet-rich fibrin membrane in descemetocele. Cornea. 35: 1245- 1249.

Choukroun, J., Diss, A., Simonpieri, A., Girard, M. O., Schoeffler, C., Dohan, S. L., Dohan, M. D. 2006. Platelet-rich fibrin (PRF): A second generation platelet concentrate. Part IV: clinical effects on tissue healing. Oral Surg. Oral Med. 101: e56-e60.

Demir, A., Erdikmen, D.O., Sevim, Z.T. and Altundag, Y. 2022. The use of an autologous platelet-rich fibrin (PRF) membrane for the treatment of deep corneal ulcers in dogs. Vet. Arh. 92: 443- 458.

Jose, C., Anoop, S., Venugopal, S.K. and Amma, T.S. 2013. Collagen sheet as an extracellular matrix scaffold for the management of corneal ulcers in dogs. Indian J. Canine Pract. 5: 171.

Kang, Y.H., Jeon, S.H., Park, J.Y., Chung, J.H., Choung, Y.H., Choung, H.W., Kim, E.S. and Choung, P.H. 2011. Platelet-rich fibrin is a bioscaffold and reservoir of growth factors for tissue regeneration. Tissue Eng. Part A. 17: 349-359.

Syam, K. V., Anoop, S. and Martin, J. K. D. Management of exposure keratopathy and corneal ulceration in Chinese pugs. Proceedings of the 23rd Kerala Science Congress, 29th to 31st January, 2011, Thiruvananthapuram. Kerala Science Congress, Centre for Earth Science Studies. 23. 199-203.

Venugopal, S.K. 2013. Management of exposure keratopathy and corneal ulceration in buphthalmic dogs. Indian J. Canine Pract. 5: 28.

Cite this article

Ajin S. K, Venugopal, S.K., Ramankutty, S., Philip, L. M., John martin, K.D. and Prasanna, K.S. 2024. Management of deep corneal ulcer in a dog using autologous platelet rich fibrin (PRF) membrane. J. Vet. Anim. Sci. 55(2):312-316

DOI: https://doi.org/10.51966/jvas.2024.55.2.312-316

Views
7
Downloads
4
Citations