Volume: 55 Issue: 2
Year: 2024, Page: 374-379, Doi: https://doi.org/10.51966/jvas.2024.55.2.374-379
Received: Oct. 16, 2023 Accepted: Feb. 23, 2024 Published: June 30, 2024
Bitches carrying a single pup can be considered as high-risk pregnancy with a greater risk of uterine inertia and obstructive dystocia. Successful management of singleton pregnancies in dogs requires early identification of the condition and the implementation of a safe and effective management plan that minimises negative effects on both the mother and the newborn. The present study investigated the efficacy and safety of a combination of progesterone receptor antagonist, mifepristone and prostaglandin E1 analogue, misoprostol in induction of whelping in six bitches with singleton litter. All the bitches in the treatment group successfully whelped viable puppies (100 per cent) with no clinical intervention, whereas the spontaneously whelped bitches with single pup was associated with a greater number of still births (50 per cent) and clinical interventions (100 per cent).
Keywords: Single pup syndrome, mifepristone, misoprostol
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© 2024 Ayana et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Ayana, C.I., Jayakumar, C., Simon, S., Becha, B. and Kariyil, B.J.2024.Medical management of canine high-risk pregnancies with single pup syndrome. J. Vet. Anim. Sci. 55(2):374-379
DOI: https://doi.org/10.51966/jvas.2024.55.2.374-379