Volume: 55 Issue: 2
Year: 2024, Page: 304-311, Doi: https://doi.org/10.51966/jvas.2024.55.2.304-311
Received: Sept. 8, 2023 Accepted: Jan. 23, 2024 Published: June 30, 2024
The current research work was undertaken to study the occurrence and pathology of cutaneous tumours in dogs and their age, breed, location and gender-wise distribution. A total of 33 samples suspected of cutaneous tumours were collected from the cases presented to Teaching Veterinary Clinical Complex (TVCC), Pookode, Wayanad, Kerala during a period of 12 months from June 2022 to June 2023. Based on histopathology, most of the tumours were diagnosed as benign. Majority of the tumours were of mesenchymal origin. Among different histological types, highest occurrence was that of squamous cell carcinoma (SCC) and trichoblastoma followed by histiocytoma, lipoma, mast cell tumour, hepatoid gland adenocarcinoma and haemangioma. Although, the incidence was higher among males and among the dogs belonging to the age group of 5-10 years, it was not statistically significant. Among different breeds, highest occurrence was observed in Labrador Retriever followed by German Shepherd. The study also warrants large scale epidemiological studies to identify the risk factors and to unravel the etiopathogenesis of canine cutaneous neoplasms.
Keywords: Cutaneous tumours, dogs, occurrence, histopathology
Avallone, G., Roccabianca, P., Crippa, L., Lepri, E., Brunetti, B., Bernardini, C., Forni, M., Olandese, A. and Sarli, G. 2016. Histological classification and immunohistochemical evaluation of MDM2 and CDK4 expression in canine liposarcoma. Vet. pathol. 53: 773-780.
Bhanderi, D.R., Jhala, S.K., Suthar, D.N., Dabas, V.S., Bhatt, A.B. and Patel, K.D. 2022. An epidemiological study of canine neoplasms. Pharma Innovation. 11: 1176-1178.
Chikweto, A., McNeil, P., Bhaiyat, M.I., Stone, D. and Sharma, R.N. 2011. Neoplastic and nonneoplastic cutaneous tumors of dogs in Grenada, West Indies. Int. Sch. Res. Notices. 2011: 1-6.
Gamlem, H., Nordstoga, K. and Glattre, E., 2008. Canine neoplasia–introductory paper. Apmis. 116: 5-18.
Goldschmidt, M.H. and Goldschmidt, K.H. 2017. Epithelial and melanocytic tumours of the skin. In. Meuten D.J. (ed.), Tumors in Domestic Animals. (5th Ed.). Wiley Blackwell, Danvers, pp. 88-141.
Graf, R., Pospischil, A., Guscetti, F., Meier, D., Welle, M. and Dettwiler, M. 2018. Cutaneous tumors in Swiss dogs: retrospective data from the Swiss Canine Cancer Registry, 2008–2013.Vet. Pathol. 55: 809-820.
Hemanth, I., Kumar, R., Varshney, K. C., Nair, M. G., Ramesh Kumar, B., Sivakumar, M. and Thanislass, J. 2015. Epidemiological and clinical studies on canine mammary tumours. Ind. J. Vet. Res. 24: 11-14.
Kaldrymidou, H., Leontides, L., Koutinas, A.F., Saridomichelakis, M.N. and Karayannopoulou, M. 2002. Prevalence, distribution and factors associated with the presence and the potential for malignancy of cutaneous neoplasms in 174 dogs admitted to a clinic in northern Greece. J. Vet. Med. 49: 87-91.
Karnik, M., Anjankumar, K.R., Jeevan, K., Gowda, Y., Rakshith, K., Shettar, M., Azeemullah, H.R., Yashas, R.K., Rajashekaraiah, R., Mahesh, V. and Rao, S. 2020. Incidence and histopathological studies on tumours of dog in Bengaluru, India. Int. J. Curr. Microbiol. App. Sci. 9: 747-752.
Kashyap, D.K., Tiwari, S.K., Giri, D.K., Dewangan, G. and Sinha, B. 2013. Cutaneous and subcutaneous tissue neoplasms in canines: Occurrence and histopathological studies. Afr. J. Agric. Res. 8: 6569-6574.
Kluthcovsky, L.C., de Lima Queiroz, T.N., Somensi, M., Castro, J.L.C. and Engracia Filho, J.R. 2021. Angiofibroma of the nasal cavity in a Dog: Case Report. Top. Companion. Anim. Med. 44: 100530p.
Kok, M.K., Chambers, J.K., Tsuboi, M., Nishimura, R., Tsujimoto, H., Uchida, K. and Nakayama, H. 2019. Retrospective study of canine cutaneous tumors in Japan, 2008–2017. J. Vet. Med. Sci. 81: 1133-1143.
Lafta, I.J. and Alabbody, H.H. 2020. Incidence of cutaneous and subcutaneous tumors of dogs from Baghdad city: Clinical, cytological and histopathological features. Iraqi J. Vet. Sci. 34: 129-137.
Lather, D., Nehra, V., Gupta, R.P., Jakhar, K.K., Agnihotri, D. and Chaudhary, R.N. 2014. Cutaneous haemagioma in a dog-a case report. Haryana Vet. 54: 89-90.
Machado, G.A.C., Fontes, T.N., Larangeira, D.F., Estrela-Lima, A., Moreira, E.L.T., Ribeiro, L.S., Pinto, M.P.R. and Peixoto, T.C. 2018. Incidence of skin tumors in dogs in Salvador, Bahia state, Brazil (2007-2016). Pesqui Vet Bras. 38: 2146– 2149.
Martins, A.L., Canadas-Sousa, A., Mesquita, J.R., Dias-Pereira, P., Amorim, I. and Gartner, F. 2022. Retrospective study of canine cutaneous tumors submitted to a diagnostic pathology laboratory in Northern Portugal (2014–2020). Canine. Med. Genet. 9: 1-14.
Mathew, R., Sajitha, I.S., Nair, S.S., Krishna, B.D., Devi, S.S. and Abraham, M.J. 2020. A Study of occurrence, gross and histopathological characteristics of canine cutaneous neoplasms. Indian J. Anim. Res. 54: 1367-1372.
Mukaratirwa, S., Chipunza, J., Chitanga, S., Chimonyo, M. and Bhebhe, E. 2005. Canine cutaneous neoplasms: prevalence and influence of age, sex and site on the presence and potential malignancy of cutaneous neoplasms in dogs from Zimbabwe. J. S. Afr.Vet. Assoc. 76: 59-62.
Nair, S.S., Narayanan, M.K., Anoop, S., Krishna, B.D., Usha, N.P. and Martin, K.J. 2021. Occurrence of canine mammary and skin/subcutaneous neoplasms in and around Thrissur district of Kerala during 2017-2020: a review of 265 cases. J. Vet. Anim. Sci. 52: 350-356.
Rafalko, J.M., Kruglyak, K.M., McClearyWheeler, A.L., Goyal, V., Phelps-Dunn, A., Wong, L.K., Warren, C.D., Brandstetter, G., Rosentel, M.C., DiMarzio, L. and McLennan, L.M. 2023. Age at cancer diagnosis by breed, weight, sex, and cancer type in a cohort of more than 3,000 dogs: Determining the optimal age to initiate cancer screening in canine patients. Plos one. 18: e0280795.
Rungsipipat, A., Sunyasootcharee, B., Ousawaphlangchai, L., Sailasuta, A., Thanawongnuwech, R. and Teankum, K. 2003. Neoplasms of dogs in Bangkok. Thai J. Vet. Med. 33: 59-66.
Senthil, N.R., Chakravarthi, R. and Vairamuthu, S. 2020. Retrospective studies on tumor conditions in dogs over a period of four years (2014-2018). Pharma Innovation. 9: 224-227.
Shabeeba, P.M., Sajitha, I.S., Devi, S.S., Divya, C. and Nair, S.S. 2021. Histopathological study of canine hepatoid gland tumours. J. Vet. Anim. Sci. 52: 277-280.
Sharma, N., Gupta, A., Bhat, R. and Shah, O. 2018. Epidemiological studies on canine tumours in Jammu. Int. J. Livest. Res. 8: 246-254.
Simeonov, R., Dinev, I., Simeonova, G., Goranov, N., Paskalev, M., Krastev, S., Todorova, I., Chaprazov, T., Roidev, R., Borissov, I., Hubenov, H. and Dinev, D. 2011. Prevalence of canine epithelial, melanocytic and mesenchymal tumours of the skin and soft tissues: A 10-year study. Bulg. J. Vet. Med. 14: 171–178.
Subapriya, S., Pazhanivel, N., Gokulakrishnan, M., Nagarajan, B., Kavitha, S., Sumathi, D. and Vairamuthu, S. 2021. Incidence and pathology of skin tumours in dogs. Pharma Innovation. 10: 620-629.
Vascellari, M., Capello, K., Carminato, A., Zanardello, C., Baioni, E. and Mutinelli, F. 2016. Incidence of mammary tumors in the canine population living in the Veneto region (Northeastern Italy): Risk factors and similarities to human breast cancer. Prev. Vet. Med. 126: 183-189.
Yumusak, N., Caliskan, M. and Kutsal, O. 2016. Fine needle aspiration cytology (FNAC) in the diagnosis of canine hepatoid gland tumors-A comparative study with histopathology. Vet. Fak. Derg. 63: 259- 266.
© 2024 Athira et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Athira, P.N., Anoopraj, R., Hamza, P., Pradeep, M., Dhanush, K.B., Sooryadas, S., Devika, S. and George, A.J. 2024. Occurrence and pathology of cutaneous tumours in dogs. J. Vet. Anim. Sci. 55(2):304-311
DOI: https://doi.org/10.51966/jvas.2024.55.2.304-311