Journal of Veterinary and Animal Sciences

Volume: 55 Issue: 3

  • Open Access
  • Research Article

Qualitative phytochemical analysis of bioactive constituents in acetone extract of seeds of Hydnocarpus pentandra

Manju K. Mathew1*, N. Madhavan Unny1, Arun George1, S. Ajithkumar1, S. Suja Rani2 and V. Ramnath3

1.Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, 2.Department of Veterinary Pharmacology and Toxicology, 3.Department of Veterinary Physiology, College of Veterinary and Animal Sciences, Mannuthy, 680651, Kerala Veterinary and Animal Sciences, Wayanad, Kerala, India

Year: 2024, Page: 644-650, Doi: https://doi.org/10.51966/jvas.2024.55.3.644-650

Received: May 13, 2024 Accepted: Aug. 5, 2024 Published: Sept. 30, 2024

Abstract

Ethnoveterinary medicine focuses on the practical use of community or area based traditional and indigenous knowledge including the collection, preparation and administration of medicinal plants or plant parts for curing diseases of animals. Hydnocarpus pentandra is a plant endemic to South India which is traditionally known for the antileprotic activity of its seed oil. Diverse pharmacological activities of the plant extracts depend on the presence of its secondary metabolites. The present research was conducted to explore the phytochemical constituents present in the acetone solvent extract of the seeds of H. pentandra. Preliminary phytochemical screening of the extract using colorimetric reactions revealed the presence of steroids, triterpenes, diterpenes, flavonoids, alkaloids and carbohydrates. Gas chromatography-mass spectrometry (GC-MS) analysis revealed the presence of different compounds which included paromomycin, D-streptamine, carnegine, 4-propyl acridine and R-limonene. The acetone extract could be considered as a potent source of new molecules with different pharmacological actions.

Keywords: Hydnocarpus pentandra, phytochemical screening, secondary metabolites

References

Alihosseini, F. and Sun, G. 2011. Antibacterial colorants for textiles. In: Pan, N. and Sun, G. (eds.), Functional Textiles for Improved Performance, Protection and Health. Woodhead publishing, Sawston, pp. 376-403.

Deepa, M.R., Dharampal, S. and Udayan, P.S. 2016. Rare, endemic and medicinal plants of selected sacred groves in Chavakkad, Thrissur district, Kerala. Asia J. Biol. Life Sci. 5(1): 78-87.

Gębka, N., Adamczyk, J., Gębka-Kępińska, B. and Mizgała-Izworska, E. 2022. The role of flavonoids in prevention and treatment of selected skin diseases. J. Pre. Clin. Clin. Res. 16(3): 99-107.

Harborne, J.B. 1998. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. (3rd Ed.). Chapman and Hall, London, 320p.

Iqbal, N., Reeta, Ahluwalia, V., Agrawal, A., Dubey, S., Kumar, J. and Dubey, S. 2023. Medicinally important natural bioactive compounds for leishmaniasis treatment: efficient alternate of toxic drugs. In: Atta-ur-Rahman (ed.), Studies in Natural Products Chemistry. Elsevier B.V., Amsterdam, pp. 247-297.

Jacobsen, P.L. and Levy, L. 1973. Mechanism by which hydnocarpic acid inhibits mycobacterial multiplication. Antimicro. Agents Chemother. 3(3): 373-379.

Patel, S.S. and Savjani, J.K. 2015. Systematic review of plant steroids as potential anti-inflammatory agents: Current status and future perspectives. J. Phytopharmacol. 4:(2): 121-125.

Sahoo, M.R., Dhanabal, S. P., Jadhav, A.N., Reddy, V., Muguli, G., Babu, U.V. and Rangesh, P. 2014. Hydnocarpus: An ethnopharmacological, phytochemical and pharmacological review. J. Ethnopharmacol. 154: 17-25.

Suhas, S. N. and Vilas, D.V. 2014. Pharmacognostic evaluation of dried leaf powder of Cardiospermum halicacabum Linn. and dried seed hull powder of Hydnocarpus pentandra (Buch.- Ham,) Oken. Int. J. Res. Ayurveda Pharm. 5(4): 502-507. 

Swayze, E.E., Griffey, R.H. and Bennett, C.F. 2007. Nucleic Acids (Deoxyribonucleic Acid and Ribonucleic Acid). In: Taylor, J.B. and Triggle, D.J. (eds.), Comprehensive Medicinal Chemistry II. Elsevier science, Amsterdam, pp.1037-1052.

Thawabteh, A., Juma, S., Bader, M., Karaman, D., Scrano, L., Bufo, S.A. and Karaman, R. 2019. The biological activity of natural alkaloids against herbivores, cancerous cells and pathogens. Toxins. 11(11): 656.

Vardanyan, R.S. and Hruby, V.J. 2006. Synthesis of Essential Drugs (1st Ed.). Elsevier science, Amsterdam, 634p.

Webster, D., Taschereau, P., Belland, R.J., Sand, C. and Rennie, R.P. 2008. Antifungal activity of medicinal plant extracts; preliminary screening studies. J. Ethnopharmacol. 115: 140-146.

Cite this article

Manju, K.M., Madhavan Unny, N., Arun, G., Ajithkumar, S., Suja Rani, S. and Ramnath, V. 2024. Phytochemical analysis of acetone extract of seeds of Hydnocarpus pentandra. J. Vet. Anim. Sci. 55 (3):644-650

Views
42
Downloads
18
Citations